林靜雯

1. 職稱：研究員 2. 學(xué)歷：博士 3. 研究方向： 運(yùn)用系統(tǒng)免疫學(xué)方法研究機(jī)體對(duì)包括瘧疾在內(nèi)傳染病的反應(yīng)；利用系統(tǒng)生物學(xué)手段及基因修飾技術(shù)研究篩選新藥、疫苗靶點(diǎn)。 4.郵箱：lin.jingwen@scu.edu.cn 5. 個(gè)人經(jīng)歷 2016年12月－至今，四川大學(xué)華西第二醫(yī)院研究員 2013年3月－2016年10月，UKMedical Research Council Career Development Fellow，The Francis Crick Institute (原National Institute forMedical Research)，英國(guó) 2008年10月－2013年2月，博士，LeidenUniversity Medical Center，荷蘭 6. 代表論文： (1) ? ? ? ? Lin JW*, Sodenkamp J, Cunningham D, et al,Langhorne J* (2017). Signatures of malaria-associated pathology revealed byhigh-resolution whole-blood transcriptomics in a rodent model of malaria. Sci Rep. (co-corresponding authors). (2) ? ? ? ? Brugat T, Reid AJ, Lin JW, etal (2016). Antibody-independentclonal selection regulates the establishment of chronic Plasmodium infection. NatureMicrobiology. (3) ? ? ? ? Capuccini B, Lin J,Talavera-López C, et al (2016). Transcriptomic profiling of microglia revealssignatures of cell activation and immune response, during experimental cerebralmalaria. Sci Rep. (4) ? ? ? ? Lin JW, Spaccapelo R, Schwarzer E, et al(2015). Replication of Plasmodium inreticulocytes can occur without hemozoin formation, resulting in chloroquineresistance.J Exp Med. (5) ? ? ? ? Salman AM,Mogollon CM, Lin JW, et al (2015).Generation of transgenic rodent malaria parasites expressing human-malariaparasite proteins. Methods Mol Biol. (6) ? ? ? ? Lin JW, Shaw TN, Bouchier P, et al (2014) Thesubcellular location of ovalbumin in Plasmodiumberghei blood stages influences the magnitude of T-cell responses. Infect Immun. (7) ? ? ? ? Ezougou CN,Ben-Rached F, Moss DK, Lin JW, et al(2014) Plasmodium falciparum Rab5B isN-terminally myristoylated and targeted to the parasite’s plasma and foodvacuole membranes. PLoS One. (8) ? ? ? ? Lin JW, Meireles P, PrudêncioM,et al (2013) Loss-of-function analyses definesvital and redundant functions of the plasmodium rhomboid proteasefamily. Molecular Microbiology. (9) ? ? ? ? Annoura T,van Schaijk BCL, Ploemen IHJ, Sajid M, LinJW, et al (2013) New members

運(yùn)用系統(tǒng)免疫學(xué)方法研究機(jī)體對(duì)包括瘧疾在內(nèi)傳染病的反應(yīng)；利用系統(tǒng)生物學(xué)手段及基因修飾技術(shù)研究篩選新藥、疫苗靶點(diǎn)。